ELEVATED GENTAMICIN LEVELS IN PREMATURE/AZOTEMIC NEWBORNS

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Evaluation of urinary enzymes in newborns treated with gentamicin

Objective(s): In recent years, there has been an increasing amount of study on early diagnosis of kidney injury through sensitive and specific biomarkers. We examined the practical applicability of the urinary levels of NAG (N-acetyl-β-D-glucosaminidase), AP (alkaline phosphatase), and LDH (lactate dehydrogenase) as renal dysfunction screening biomarkers in full and pre-term newborns treated wi...

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Population pharmacokinetics of gentamicin in premature newborns.

OBJECTIVES To determine the pharmacokinetic parameters of gentamicin in a population of 200 premature newborns and to investigate the influence of several clinical and physiopathological covariates on the pharmacokinetics of the drug. To validate the pharmacokinetic analysis performed in another population of 50 premature newborns. METHODS A total of 200 premature newborns were evaluated at t...

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Evaluation of urinary enzymes in newborns treated with gentamicin

OBJECTIVES In recent years, there has been an increasing amount of study on early diagnosis of kidney injury through sensitive and specific biomarkers. We examined the practical applicability of the urinary levels of NAG (N-acetyl-β-D-glucosaminidase), AP (alkaline phosphatase), and LDH (lactate dehydrogenase) as renal dysfunction screening biomarkers in full and pre-term newborns treated with ...

متن کامل

evaluation of urinary enzymes in newborns treated with gentamicin

objective(s): in recent years, there has been an increasing amount of study on early diagnosis of kidney injury through sensitive and specific biomarkers. we examined the practical applicability of the urinary levels of nag (n-acetyl-β-d-glucosaminidase), ap (alkaline phosphatase), and ldh (lactate dehydrogenase) as renal dysfunction screening biomarkers in full and pre-term newborns treated wi...

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Elevated levels of serum sICAM-1 in asphyxiated low birth weight newborns

Perinatal hypoxia results in neuronal and endothelial cell damage. The main purpose of this study was to investigate the correlation of soluble intercellular adhesion molecule 1 (sICAM-1) expression and peripheral blood changes in perinatal asphyxia with neuronal injury markers in low birth weight (LBW) neonates. We compared the concentrations of serum sICAM-1, neuron-specific enolase (NSE) and...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 1977

ISSN: 0031-3998,1530-0447

DOI: 10.1203/00006450-197704000-00318